Mixing meaning into disease research – Treato

I wasn’t so sure how to describe Treato. It’s really interesting – mixing semantic analysis, social media, medical records, and analysis – Treato is really the next level of how consumers research diseases. The image to the right is one that came from searching for Lyme disease. I am not sure how they assemble that […]

Big Data, healthcare, devices, and quantified self

When I was at SXSW, I spent most of my time at either Big Data or Healthcare sessions. The interesting thing is that the Big Data sessions always devolved to talking about healthcare and the healthcare sessions always spoke about Big Data. One aspect of the fusion of big data and healthcare that kept coming […]

The Impact of a Consortium of Fermented Milk Strains on the Gut Microbiome of Gnotobiotic Mice and Monozygotic Twins

“The results also showed that (i) consumption of an FMP containing five bacterial strains was not associated with a statistically significant change in the proportional representation of resident community members within and between individuals; (ii) the appearance and disappearance of strains comprising the FMP consortium did not exhibit familial patterns in the fecal microbiota; and […]

Dangerous C. difficile infections soar in US, but Massachusetts hospitals have cut germ’s spead – The Boston Globe

“A life-threatening germ that causes diarrhea and spreads easily from doctors’ offices to hospitals and nursing homes has climbed to historic highs nationally, federal disease trackers warned Tuesday, as they pointed to efforts in Massachusetts that have helped slow the rate of infections here.” More on this nasty bug. It’s now getting headlines. Read this […]

A Method for Generation Phage Cocktail with Great Therapeutic Potential – PLoS ONE

“Bacteriophage could be an alternative to conventional antibiotic therapy against multidrug-resistant bacteria. However, the emergence of resistant variants after phage treatment limited its therapeutic application. Our data showed that the phage cocktail was more effective in reducing bacterial mutation frequency and in the rescue of murine bacteremia than monophage suggesting that phage cocktail established by […]

Macro and Micro Diversity of Clostridium difficile Isolates from Diverse Sources and Geographical Locations – PLoS ONE

“Clostridium difficile has emerged rapidly as the leading cause of antibiotic-associated diarrheal disease, with the temporal and geographical appearance of dominant PCR ribotypes. We have undertaken a breadth genotyping study using multilocus sequence typing (MLST) analysis of 385 C. difficile strains from diverse sources by host (human, animal and food), geographical locations (North America, Europe […]

Influence of Milk-Feeding Type and Genetic Risk of Developing Coeliac Disease on Intestinal Microbiota of Infants: The PROFICEL Study

“This study demonstrates that the milk-feeding type and the HLA-DQ genotype differently influence the bacterial colonization pattern of the newborn intestine during the first 4 months of life and, therefore, could also influence the risk of developing CD in later life. Breast-feeding reduced the genotype-related differences in microbiota composition, which could partly explain the protective […]