links for 2009-11-27

Video: DIYBio meetup 22nov09

We had a DIYbio Cambridge Boston Sommerville meetup this past weekend to get familiar with a nice new hackspace, The Sprouts, to come up with a project for the next few months, and to move and set up equipment in the current space.

The great folks at The Sprouts actually want a wet-space for DIYbiology. They gave us some space and they even had some equipment. We added to that the equipment Mac picked up from a failed biotech.

The whole moving, setting-up thing was quick. We had Kay, Mac, Manuel, Paul, Charles, Jason, and I there, so the "many hands" made the work lighter.

I was happy to see things happening, space being set up, projects being set. Of the things on my to-do list, a few have been now knocked off, allowing me to join existing set-ups.

I took some video of what we were up to.

One last thing: I am so pleased with The Sprouts. They only opened in August, but show great promise. I hope that our group can be part of their growth and give back as even more than they have already so generously given us.

links for 2009-11-23

Mac, Sophia, and the philosophy of 21st-century Biology

image from www.flickr.com Mac has written two short but deep posts, inspired by a talk by Sophia Roosth. What inspired Mac was Sophia's "anthropological insight" that DIYbio is "domesticating" Biology.

While I don't feel that it's an explicit doctrine, domestication of Biology is indeed the spirit of what DIYbiologists are up to. It's something that arises from the curiosity, openness, and tinkering that represents the DIYbiolgist "ethic." Sophia puts it in terms of "episteme" (Knowing) and "techne" (Doing).

Biology, as a discipline, is young in many ways – "science" itself is a product of the Enlightenment. And, as a focus of understanding, Biology is old – Aristotle was a biologist.

But domesticated Biology is at the core of civilization: thousands of years ago folks were breeding animals and plants, and brewing beer, bread, yogurt, and wine. These are the heart of Genetics and Microbiology and Biochemistry.

Mac made a recording of Sophia's talk. It's brilliant and really expresses DIYbio (and synthbio) as it is today and where it can lead. It's a must-listen for anyone interested in the future of Biology.

She makes a very nice story of the mind-sets of institutional and non-institutional scientists. And she pivots around the Homebrew Computer Club analogy as a way to think of the where DIYbio is going.

In many ways, she reminds me of the talks Dana Boyd gave, back in the day, as she watched the early evolution of social networking – Sophie brings together a range of threads from different disciplines to provide some coherence and understanding of the events and thinking unfolding right in front of us. Sophie has articulated what DIYbiologist just knew, just "did," in their hearts.

I think her insights just accelerate the nucleation of the "movement" at these early stages of exploration.

Go listen to it.

Image from pusgums

links for 2009-11-19

links for 2009-11-18

“The Machinery of Life” – a great book for molecularly-minded folks

MoL2-cover I've been meaning to share this for the longest time. I've had this book for ages and never tire of it.

"The Machinery of Life," by David Goodsell, is an illustrated journey through cells and proteins and macromolecules – at scale.

What I like about the book is that it attempts to show what it really looks like if you're the size of a molecule – the crowding, the relative sizes, and so on.

It's a really fascinating book for someone like me who has his head in the (molecular) clouds. 🙂

There is a review of the original edition (PDF). A nice phrase from that review was "cellular numeracy," referring to the way Goodsell places things in scales, making us realize the relative sizes of molecules and cells.

At the iGEM Jamboree I saw a color image from Goodsell. After searching a bit, I now know that there is a color edition of the book (just out in 2009?), updated with new molecules, too. You can see more on Goodsell's own pages at Scripps.*

I highly recommend this book for anyone messing with molecules, to get a good idea of what the macromolecular landscape truly looks like.

Enjoy!

*It's a shame that the Scripps pages are so 1999-ish. The site needs to be more visual and more up to date.

links for 2009-11-17