Three trends for the future of biology

AtgctA chance encounter, about a year ago, with some interesting minds in the field of biomedical publishing had me going back to my roots: biology. I’ve been fascinated by science from a young age, particularly biology, which I studied and practiced for many years before a wormhole whisked me away and plopped me in the middle of the mobile phone industry.

The consequence of this chance encounter with biologists was for me to reconnect and catch up with what was happening in biology. I really don’t know if my fresh eyes are actually seeing something new or if my absence has made me susceptible to an incomplete model of where biology is going. In any case, what I do see are some exciting developments.

To get to the point, I see three major biology trends that present enormous opportunities:

1) Synthetic biology – from crafting whole genomes to messing with computational biology, we are seeing a renaissance of microbiology and microbial genetics.

2) Personal genomics – as genomic analysis tools like sequencing machines and micro-arrays get cheaper, the ability to rapidly analyze ones own genome at some level becomes a reality.

3) Biological publishing – the sheer volume of scientific publications and data, and their increasing availability in open access digital formats, is straining the way scientists explore, syncretize, and contribute to knowledge. [I need to find a better term for this, as it’s not about publishing but the whole cycle of the info.]

These three areas have been consuming a lot of my brain cycles, with resultant decrease in posting the thoughts down here. I suppose I needed to mull these things over before starting to haver about them.

I thought I was ready to knock these off but have been having a fun time following the cognections radiating off from these topics. I have a lot of bookmarks with partially read stories. So, further posts on these topics will come slowly as I continue to digest.

Wow. It’s nice to use one’s brain.

Image from ynse

Cool animation by 23andMe on Human Prehistory

23Andme - Human Prehistory  PrologueFor various reason I’ve been lurking around 23andMe, a personal genetics social service thingy out of SFO (I follow them on Twitter, of course). One big part of what they do is basic education on genetics, what it means, how its done, and its place in our understanding of who we are.

They’ve made a really cool animation of human prehistory, from chimps to homo sapiens (link below).

Looking forward to the next chapter.

Link: 23andMe – Human Prehistory: Prologue

Image from the animation

Eye opening: Opera’s latest State of the Mobile Web report

When I see stuff like this I feel ashamed for ever thinking Africa’s use of mobile was any ‘less’ sophisticated than Europe or Asia.

I keep reminding myself of the rise of photo sharing in Brasil, the use of mobile sites like MOSH and Winksite in India, and the number of hits nokia.mobi gets from China.

Forget the ringtone-wallpaper part of the mobile services cycle. These folksk are leapfrogging right to browsing and more interactive internet-connected apps.

Link: Eyes on Africa: Mobile Web use surges in Africa according to Opera’s latest State of the Mobile Web report

Fast facts

  • The use of Opera Mini in Africa increased by 180 percent from January 2008 – September 2008
  • Globally, Opera Mini was used by 19 million people in September 2008, a 341 percent increase from September 2007
  • Opera Mini users accessed 4.5 billion pages in September 2008, a 420 percent increase from September 2007
  • In September, Opera Mini’s 19 million users generated more than 65.2 million MB of data for operators worldwide
  • Egypt is now the tenth largest user of Opera Mini in the world

Where I’ve spoken, where I will speak

Here’s a list of some public talks I’ve given or panels I’ve been on over the past few years.

2011
Healthcare New Media Marketing conference (Chicago, 23-24 May 2011) – Speaker: “Effective Healthcare UseFacebook: The Social Network of Continued Success” Panelist: “Great Information, but Now What? Putting Social Media Tools to Use”

Ingite Amherst (Amherst, 08 Feb 2011) – Speaker

2010
Babson’s Healthcare & Life Sciences Industry Forum (Wellesley, 15 April 2010) – Moderator. Panel on the impact of social media on health care.
DIYBio and Synthbio roundtable (UMass Amherst, 07 April 2010) – An open discussion on DIYbio, Synthetic biology, and how it impacts institutional science.

2009
next conference 2009 (Hamburg, 05-06 May 2009) – Speaker. Mobile trends. [Video] Marketing 2.0 Conference (30-31 March 2009) – Speaker. Social Media.
3rd WLE Mobile Learning Symposium (London, 27 March 2009) – Keynote [Notes. Presentation. Related video.]European Patent Office (Munich, 03 March 2009) – Speaker. Social Media.
Digital Lifestyle Days (Munich, 25-28 January 2009)- Speaker [Video of panel]

2008
New Media Days (Copenhagen, 08-09 October 2008) – Panel on mobile media
Mobile 2.0 Europe (Barcelona, 04 July 2008) – Panel on mobile social media

2007
mLearn – (Melbourne, 17-19 October 2007) – Keynote – ‘The Mobile Lifestyle: How the fusion of the mobile and the Internet have changed the way we live, learn, and play.’ Also, on closing panel.

2006
Le Web 3 – (Paris, 10-11 December 2006) – Ended up on the panel on mobile 2.0 and mobile social networking (two panels combined).

2005
Les Blogs 2 (Paris, 05-06 December 2005) – I was on the panel “Closing session: the future” (video)
Europe Direct Marketing (Berlin, 11-12 May 2005) – Keynote on blogging
Les Blogs (Paris, 25 April 2005) – Opening panel on “Where are we going?”


(updated: 25mar10)

Does paying off the creditors undermine social trust?

GiftVia a few people I went and read Margaret Atwood’s Op-Ed in the NYT (link below) about debt and its role in society. Nice read. For me the most interesting thing is the word for ‘debt’ and ‘sin’ are the same in Aramaic (see quote below). That turns ‘sin’, something to be ashamed of and a violation of something beyond society, to ‘debt’, something you owe the people around you – much more accountable.

Leads me to thoughts about different shame and guilt mechanisms some societies have, say Catholic vs Lutheran.

Hm.

In a related topic, did you know that even monkeys understand fairness (the basis for debt and credit)?

There was an experiment where they gave two (rhesus?) monkeys cucumber slices. No problem. But, then they started giving one of them a grape (much tastier). The one with the cucumber slice threw it back in apparent anger for being treated unfairly.

In another story, this guy got mauled by some chimps who were jealous of the attention (and cake) he had been giving another chimp (the guy was the chimps previously adoptive human parent). The angry chimps just thought it was plainly unfair not to share the cake.

Yeah. I think so much of our massive brain is geared to keeping (up to 150?) various combinations of relationships and debt-credit arrangements. Indeed, the whole human social system is based on tit for tat and retribution for those who violate this necessary social flow.

What do you think?

Link: Op-Ed Contributor – A Matter of Life and Debt – NYTimes.com

Once you start looking at life through these spectacles, debtor-creditor relationships play out in fascinating ways. In many religions, for instance. The version of the Lord’s Prayer I memorized as a child included the line, “Forgive us our debts as we forgive our debtors.” In Aramaic, the language that Jesus himself spoke, the word for “debt” and the word for “sin” are the same. And although many people assume that “debts” in these contexts refer to spiritual debts or trespasses, debts are also considered sins. If you don’t pay back what’s owed, you cause harm to others.

Image from Chrys Omori

Gah. Why are folks trying to be digital in an analog world?

Call me old-fashioned, but I want some analog-computing being done with biological systems. I’m never comfortable with digital thinking with biological macromolecules. On-off systems built on chemical concentrations and macromolecular binding just don’t seem to make sense to me.

Eh, there are folks doing this who are smarter than me, so I suppose I need to see more systems built to teach the point to me.*

Link: RNA-based logic gates compute inside cells

Detecting tetracycline isn’t especially interesting, but RNA that binds to specific small molecules is actually relatively easy to make; repeated rounds of amplification and selection for binding can evolve these RNAs in a couple of days. This means that, in a matter of days, researchers can grow yeast colonies that glow in response to a variety of chemicals, or even to combinations of chemicals.

*Really bummed out that I will be missing _another_ Long Now talk (I’m in SFO two weeks prior). Especially this one with Drew Endy, bio-engineer extraordinaire. I was so looking forward to meeting him. Oh, well. Thank goodness for the video feed.

The most famous pillow book of the 20th century is getting revised

Here’s a great article (link below) on the book “The Joy of Sex,” which is getting updated for the 21st century (and women).

It’s really interesting to think of the world that gave birth to the book compared to the world we live in now. The old book is full of interesting stuff, but feels quite anachronistic, both in style and attitude. An update is indeed due.

In so many ways, I aso think a book like this is still needed to loosen up the tensions that still exist when talking, thinking, and having sex. Folks are still so stuck up.

Looking forward to the new edition.

Link: Revising the 20th century’s most famous sex manual – The Boston Globe

WHAT WAS THE most influential book of the 20th century? Perhaps you’d vote for “Relativity,” by Albert Einstein. But for my money, the book that blew the lid off the century could only be “The Joy of Sex.”

Do media endorsements of candidates mean anything

I’ve been watching Obama rack up the endorsements. But, a quick check of the last presidential election shows that Kerry far outstripped Bush in getting endorsements from major news outlets (and including a huge number of folks who endorsed Bush in 2000).

Do endorsements make sense any more?

Link: 2004 Media Endorsements – dKosopedia

As of 10/26, our list below represents 97 endorsements for Kerry, 58 for Bush, and 6 who declined to endorse. Of the Kerry endorsements, 25 (25.8%) endorsed Bush in 2000, and 49 (50.5%) endorsed Gore in 2000. Of the Bush endorsements, 38 (65.5%) endorsed Bush in 2000, and 4 (6.9%) endorsed Gore in 2000. Of the “Declined” endorsements, 6 (100%) endorsed Bush in 2000. Using these figures, Kerry holds a 6-to-1 advantage over Bush in endorsement switchers, however that doesn’t include the 6 papers that switched from Bush to nobody which E&P does not track. If you include those, then it’s an 8-to-1 advantage.

Political and economic turmoil driving info-obsession

Ok. But, are we just passive? Has there been an uptick in activism as well?

Link: Too Much News? – NYTimes.com

And the news is not just consequential, but whipsaw-volatile. Financial markets swing hundreds of points within an hour; poll numbers shift. This means that news these days has an unbelievably short shelf life, news addicts said. If you haven’t checked the headlines in the last half-hour, the world may already have changed.

(and why does the NYT always have a gratuitous link to the Jeebus-phone?)