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Author: charlie

Links of note/Science/Strategy/The Narrative

The wacky world of horizontal gene transfer, genomic variants, and what we think are microbial species

Posted on 20 April 2012 by charlie

“The main difference from eukaryotes is that prokaryotic reproduction is independent of DNA acquisition and recombination. Instead, DNA is obtained from f...

Links of note/Strategy/The Narrative

Another article on “Patterns of Early Gut Colonization Shape Future Immune Responses of the Host” in PLoS ONE

Posted on 17 April 2012 by charlie

“In conclusion, a time window exists that enables the artificial colonization of GF mice by a single oral dose of caecal content, which may modify the fut...

Links of note/Strategy/The Narrative

New Old Publishing and “The New Value of Text”

Posted on 11 April 2012 by charlie

“Finally, the text still requires context. As publishers spin up their digital and print-on-demand backlists, more and more is published with less and les...

Innovation/Links of note/Science/Strategy/The Narrative

Gut microbes and immunity: The hygiene hypothesis, peak antibiotics, and the post-Pasteurian Age

Posted on 09 April 2012 by charlie

“Exposure to microbes during early childhood is associated with protection from immune-mediated diseases such as inflammatory bowel disease (IBD) and asth...

Links of note/Science

The Impact of a Consortium of Fermented Milk Strains on the Gut Microbiome of Gnotobiotic Mice and Monozygotic Twins

Posted on 06 April 2012 by charlie

“The results also showed that (i) consumption of an FMP containing five bacterial strains was not associated with a statistically significant change in th...

Links of note/Science/The Narrative

International Human Microbe Program Looks Ahead – ScienceInsider

Posted on 30 March 2012 by charlie

Indeed, Sharp said at the meeting, patients who come to Cleveland Clinic for treatment of inflammatory bowel disease express their own concerns about such appro...

Science/The Narrative

Microbiome sequencing offers hope for diagnostics : Nature News & Comment

Posted on 27 March 2012 by charlie

“Jonathan Eisen [@phylogenomics], a microbiologist at University of California, Davis, is worried that microbiome research will eventually encounter the s...

Links of note/Science/The Narrative

Dangerous C. difficile infections soar in US, but Massachusetts hospitals have cut germ’s spead – The Boston Globe

Posted on 23 March 2012 by charlie

“A life-threatening germ that causes diarrhea and spreads easily from doctors’ offices to hospitals and nursing homes has climbed to historic highs nation...

Links of note/Science

A human gut microbial gene catalogue established by metagenomic sequencing : Nature

Posted on 22 March 2012 by charlie

“Beyond providing the global view of the human gut microbiome, the extensive gene catalogue we have established enables future studies of association of t...

Links of note/Science

Genome Sequence of E. coli O104:H4 Leads to Rapid Development of a Targeted Antimicrobial Agent against This Emerging Pathogen – PLoS ONE

Posted on 22 March 2012 by charlie

“A recent widespread outbreak of Escherichia coli O104:H4 in Germany demonstrates the dynamic nature of emerging and re-emerging food-borne pathogens, par...

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