Bacterial genomics: A new source of antimicrobial targets : Nature Reviews Microbiology
“Bacterial clone-based genome sequencing frequently results in gaps, which harbour hypothetical genes of unknown function. Sorek and colleagues show that ...
Author: charlie
A Method for Generation Phage Cocktail with Great Therapeutic Potential – PLoS ONE
“Bacteriophage could be an alternative to conventional antibiotic therapy against multidrug-resistant bacteria. However, the emergence of resistant varian...
Macro and Micro Diversity of Clostridium difficile Isolates from Diverse Sources and Geographical Locations – PLoS ONE
“Clostridium difficile has emerged rapidly as the leading cause of antibiotic-associated diarrheal disease, with the temporal and geographical appearance ...
Broad Institute Gets $32.5 Million to Map Cell Circuits – ScienceInsider
“The Broad isn’t alone: Mount Sinai School of Medicine in New York City, the Allen Institute for Brain Science in Seattle, the Salk Institute in San...
Two-Drug Antimicrobial Chemotherapy: A Mathematical Model and Experiments with Mycobacterium marinum – PLoS Pathogens
This paper is trying to measure and model the effectiveness of multi-drug antimicrobial chemotherapy. Antibiotics are notorious for losing effectiveness as the ...
Patterns of Gene Flow Define Species of Thermophilic Archaea: PLoS Biology
“Patterns of homologous gene flow among genomes of 12 strains from a single hot spring in Kamchatka, Russia, demonstrate higher levels of gene flow within...
Influence of Milk-Feeding Type and Genetic Risk of Developing Coeliac Disease on Intestinal Microbiota of Infants: The PROFICEL Study
“This study demonstrates that the milk-feeding type and the HLA-DQ genotype differently influence the bacterial colonization pattern of the newborn intest...
Crowd-Sourcing Drug Discovery
“The first challenge that OSDD’s cyber-community assigned itself was to glean more information from the M. tuberculosis genome. It was sequenced in ...
Biodiversity of Indigenous Saccharomyces Populations from Old Wineries of South-Eastern Sicily: Preservation and Economic Potential
“We report on the remarkable degree of biodiversity in the wine yeast populations naturally present in a small area of Sicily where traditional (non-indus...
Vaccine development: Man vs MRSA : Nature News
“For decades, Robert Daum has studied the havoc wreaked by methicillin-resistant Staphylococcus aureus. Now he thinks he can stop it for good.” Exce...