Institutional science needs to change

image from www.flickr.com I was having lunch with some old ex-lab friends. Unlike me, who left the lab at the end of the 90s, all three of them have kept on doing research and medicine and have their own labs with students, post-docs, and techs. The good news is that their research is progressing, the bad news is that funding is tighter than ever.

I had asked them who was writing a grant (of course, knowing that one always is writing some grant). There was an awkward pause as all three of them seemed to be lost in their thoughts, then they gave me an update of where things were at, since last I was in science, listing some stats to show how things were getting tighter.

When I left research, I had the naïve idea that I would no longer need to hustle for money. But, we all know, the biz world is just the same. Yet, for sure, the biz world seems to have a multitude of revenue and funding options that don't seem to be available to institutional scientists.

I feel that the whole endeavor of Science (I come from a biology background, so my thoughts are around that area, really) has been stuck in the 60s – the way we fund science, the expectations of the apprenticeship (PhD and Postdoc), the publishing and reputation cycle, the job progression – all seem to have been built in a model that came into being in the science boom of the 50s and 60s and really hasn't changed.

Am I missing something? I've been out 10 years, but it seems like nothing has improved. Funding is tighter, people still can't get academic jobs, and publishing is getting more onerous.

How do I envision the future of institutional science?

I'm not sure.

I've mentioned how science publishing could change, taking cues from the current way we use the Social Web. I think DIYBio points to how science could change how we explore the natural world and who does it. And, brilliant folks, like at Biocurious and Pink Army Coop, are looking at ways to diversify how we fund and participate in funding the future of science.

In summary, the business of institutional science is sclerotic and the clues to how we move forward are right in front of us. And, as usual, institutional culture is in the way of this change.

Do you think the way we do science should change? Can it? Will it in our lifetime? How do you envision the future of science or are we fine the way we are?

Image by caterina

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Hacking microscopes – DIYBio meetup 13dec09

image from www.flickr.com We had another gathering at The Sprouts. Mac, Jason, Jason, Dave, Kay, and I (with my son) gathered and talked about moving forward with safety stuff (pages, FAQs, and questionnaires), logo stuff, and playing around webcams.

We were going to do some wet-work, but the webcam seemed more interesting and we played with them, building a set up to see if we can use them like the folks at Hackteria.org did. In the process, we ended up taking microscopes apart so that we could have more fine control over the height of the slide.

Kinda funny to break up microscopes to build one.

Here are some pics of the afternoon (no video this time):

Book review: The Manga Guide to Molecular Biology

Mg_mbiology_big I had the good fortune of being sent a book by No Starch Press called "The Manga Guide to Molecular Biology." The book is a great introductory molecular biology text book explained through a manga-style narrative.

On the story side, it is very funny. Two girls, have been sent to their professor's private island for summer school. Under his and his assistant's tutelage, the girls gradually learn about proteins, DNA, transcription, and molecular cellular processes. The girls use a virtual reality machine to see molecules and processes up close and their string of questions serve to make the reader think through the topics.

Of course, as part of the girls' growth through the book, tempers flare, jokes are made, and embarrassing situations crop up – all drawn in manga style.

The narrative serves well to walk the reader though the topics, especially since the girls themselves have an inkling about the subject but are discovering it more in depth. Also, the topics, to me, seemed quite compete. The drawings and explanations alternate with pages of expository text (sprinkled with dialogue) to move between a high-level view and some detail.

It may not be "Genes," which I used in grad school, but it's a very good introductory text. I handed it to my son, who is in high school, and it has been helpful to him in his biology projects (and I think he found the storyline quite engaging, too).

I recommend this book as a fun introductory molecular biology text book. Graphical narratives are a great way to explore science and math (check out this amazing one on Mathamatics and Logic). No Starch Press has other manga books on Stats, Databases, Physics, Electricity, and Calculus.

If you want to know more about the book, here's an excerpt. Also, below, is a video by Joanne Manaster (@sciencegoddess), reviewing the book in her own inimitable style.
The Manga Guide to Molecular Biology (Excerpt)

Book info, from the publisher, No Starch Press:

"The Manga Guide to Molecular Biology"
by Masaharu Takemura, Sakura, and Becom Co., Ltd.
August 2009, 240 pp. $19.95

ISBN-10 1-59327-202-2

ISBN-13 978-1-59327-202-9

Rin and Ami have been skipping molecular biology class all semester, and Professor Moro has had enough—he's sentencing them to summer school on his private island. But they're in store for a special lesson. Using Dr. Moro's virtual reality machine to travel inside the human body, they'll get a close-up look at the fascinating world of molecular biology.

Join them in "The Manga Guide to Molecular Biology," and learn all about DNA, RNA, proteins, amino acids, and more. Along the way, you'll see chemical reactions first-hand and meet entertaining characters like Enzyme Man and Drinkzilla, who show how the liver metabolizes alcohol.

Together with Ami and Rin, you'll learn all about:

• The organelles and proteins inside cells, and how they support cellular functions

• The processes of transcription and translation, and your genes' role in synthesizing proteins

• The pieces that make up our genetic code, like nucleotides, codons, introns, and exons

• The processes of DNA replication, mitosis and cytokinesis

• Genetic technology like transduction and cloning, and the role of molecular biology in medicine

Whether you need a molecular biology refresher or you're just fascinated by the science of life, "The Manga Guide to Molecular Biology" will give you a uniquely fun and informative introduction.

Masaharu Takemura is a Lecturer at the Tokyo University of Science in biology, molecular biology, and life sciences. A Doctor of Medical Science, Takemura has written several books about biology.